- August 1 – The twenty-one Commissioners for the University of Virginia, chaired by Thomas Jefferson, meets at the Mountaintop Inn at Rockfish Gap, not only to choose a location for the home of a new state university, but also to recommend buildings, curriculum and administrative structure. Arguing for Charlottesville’s central location and the advancing construction on the site, Jefferson, James Madison and their allies proffer the assets, land and buildings of Central College as an inducement, and the Commission chooses Charlottesville. 
- November 17 – Charlotte of Mecklenburg-Strelitz (aged 74), queen consort of Great Britain and namesake of the City of Charlottesville, at Kew Palace, Kew, England.
- Web. Serpentine Timeline, Winter 2018, retrieved April 16, 2021.